Assessment of Biosafety and Fillet-Residues After Florfenicol Exposures in Trachinotus Blochii to Ensure Safe-Applications in Disease Incidences

Trachinotus blochii is a promising mariculture fish species. Scientific data on biosafety and fillet residues of florfenicol exposure, one recommended amphenicol antimicrobial for aquaculture use, remains unknown in T. blochii, despite its criticality prudent application. Accordingly, the paper evaluated safety (regarding mortality, symptoms, weight gain, histopathology) dietary after therapeutic (10 mg Kg-1 ten days) excessive (three, five, times dose 10, 20, 30 exposures. There was no mortality any group. The clinical abnormalities were noted only 10X group from 25th exposure day, which disappeared fourth day withdrawal. Reduced growth recorded at 5X groups 20 days, respectively. Histological lesion`s severity liver > kidney gill spleen muscle intestine. lesion relied quantity duration exposures, with maximum 30th day. After below residual limit accepted by European Union (1000 μg Kg-1) three withdrawal, showing minimum three-day necessary to reach safe, acceptable level.